Research & Academic Profile
Researcher and computional biologist with experience in cancer genomics, transcriptomics and bioinformatics. Passionate about interdisciplinary work and innovation.
Get in touch01 — About
Computational biologist with deep expertise in cancer genomics and long-read multi-omics. My current research centres on characterising transcriptional diversity in lung cancer using long-read multiomic methods.
Experienced in integrating heterogeneous data modalities—including scRNA-seq, long-read RNA-seq, bulk transcriptomics, and whole-genome sequencing.
02 — Experience
Apr 2024 — Present
University College London (UCL) · Cancer Research UK Lung Cancer Centre of Excellence
Leading computational study on transcriptional diversity and isoform discovery using Oxford Nanopore long-read RNA sequencing. Developing bioinformatic pipelines for isoform quantification and differential transcript usage analysis. Supervising PhD students and contributing to grant applications.
Oct 2019 — Jan 2024
University of Cambridge & EMBL-EBI
Reconstructed cellular lineage histories and quantified clonal dynamics at single-cell resolution using phylogenetic inference and Bayesian phylodynamic modelling. Developed cell-type deconvolution approaches using single-cell RNA-seq reference atlases. Integrated multi-modal datasets to study clonal architecture and genomic-state relationships. Thesis: "Elucidating the evolutionary dynamics of MSI tumours at the single-cell level"
Jan 2019 — Jul 2019
University College London (UCL)
Identified somatic copy number alterations and structural variants from whole-genome sequencing of human brain tissue. Implemented and optimised variant-calling pipelines for large-scale WGS datasets with custom filtering scripts for somatic variant detection.
03 — Skills
Programming
Omics & Genomics
Computational Biology
04 — Education
Sep 2019 — Jan 2024
University of Cambridge & EMBL-EBI
Thesis: "Elucidating the evolutionary dynamics of MSI tumours at the single-cell level". College Senior Scholarship recipient (2020–2023).
2014 — 2018
University of Crete
Erasmus traineeship at University College London. World Hellenic Biomedical Association Scholarship (2018).
05 — Publications
Redefining cancer drivers with tissue-specific context.
Cancer Cell (in press)
Transcriptional signals of transformation in human cancer.
Genome Medicine
Transcriptional differences between JAK2-V617F and wild-type bone marrow cells in myeloproliferative neoplasms.
Experimental Hematology
Reconstructing lineage histories and differentiation trajectories of individual cancer cells in myeloproliferative neoplasms.
Cell Stem Cell
Complex mosaic structural variations in human fetal brains.
Genome Research
Investigation of somatic CNVs in brains of synucleinopathy cases using targeted SNCA analysis and single cell sequencing.
Acta Neuropathologica Communications
06 — Awards & Scholarships
College Senior Scholarship
Fitzwilliam College, University of Cambridge (2020–2023)
World Hellenic Biomedical Association Scholarship
2018